Blood–brain barrier opening to large molecules does not imply blood–brain barrier opening to small ions
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چکیده
منابع مشابه
Blood–brain barrier opening to large molecules does not imply blood–brain barrier opening to small ions
Neuroimaging of exogenous tracer extravasation has become the technique of choice in preclinical and clinical studies of blood-brain barrier permeability. Such tracers have a larger molecular weight than small ions, neurotransmitters and many drugs. Therefore, it is assumed that tracer extravasation indicates both permeability to these and the cancelation of the electrical polarization across t...
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ژورنال
عنوان ژورنال: Neurobiology of Disease
سال: 2013
ISSN: 0969-9961
DOI: 10.1016/j.nbd.2012.12.007